CD4 Antikörper
Kurzübersicht für CD4 Antikörper (ABIN206939)
Target
Alle CD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes an epitope in the D1 domain of CD4 antigen, a 55 kD transmembrane glycoprotein expressed on a subset of T lymphocytes (helper T cells) and also on monocytes, tissue macrophages and granulocytes. It is negative in Western blotting even with non-reduced samples of cell lysates.
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Aufreinigung
- Protein A purified
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Immunogen
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Human thymocytes and T lymphocytes.
Type of Immunogen: Cells -
Isotyp
- IgG2a
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Applikationshinweise
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Approved: Block, Flo, Func, Inhb, IP, Neut
Usage: Immunoprecipitation: excellent. Functional Application: The antibody MEM-115 blocks binding of HIV gp120 to CD4 Molecule and it also strongly inhibits CD4-MHC Class II interactions. Flow Cytometry: Recommended dilution - 3 μg/mL. Application notes:. Altho
Not recommended for: IHC-P -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Tris buffered saline (TBS), 15 mM sodium azide, approx, pH 8.0.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- avoid freeze thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- CD4
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Andere Bezeichnung
- CD4
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Hintergrund
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Name/Gene ID: CD4
Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule -
Gen-ID
- 920
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UniProt
- P01730
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Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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